UIBC TestingUIBC measures unsaturated transport proteins. It is used in conjunction with total serum iron to calculate the total iron-binding capacity (TIBC) and is part of an iron and TIBC panel. TIBC (µg/dL) = UIBC (µg/dL) + Iron (µg/dL) The body makes transport proteins in response to iron levels. About 30% of transport proteins are used at any given time, and the UIBC measures the unbound transport protein content. UIBC in PregnancyUIBC changes in conjunction with TIBC. Please read the TIBC article. High UIBC in PregnancyUIBC is elevated when there is iron deficiency, as it represents a large portion of unbound transport proteins and lower serum iron levels. It can also represent an elevated production of transferrin and transport proteins. Most Common Causes of High UIBC in Pregnancy
Low UIBC in PregnancyA low UIBC occurs when there is more than adequate iron in the bloodstream but the transport proteins have a reduced availability to bind additional iron. This can be due to iron excess or a reduced production of transferrin. Most Common Causes of Low UIBC in Pregnancy
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Hi There!I'm Sarah Thompson, the author of Functional Maternity, and the upcoming book Beyond Results - A practitioner's Handbook to Effective Functional Lab Analysis in Pregnancy. Lab Tests
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